Abstract:
2(5)-Substituted 4-hydroxy-3,4-diphenylcyclopent-2-en-1-ones easily react with 2.5 molar excess of maleic anhydride to give 1(4)-substituted 7,8-diphenylbicyclo[2.2.2]oct-7-ene-2,3,5,6-tetracarboxylic acid dianhydrides containing alkyl groups at bridgehead of the bicycle. The stereochemistry of the obtained bicyclic bis-anhydrides was determined to be syn-syn.
Document Type:
Article
Language: English
Citation:
I. V. Mikhura, A. A. Formanovsky, E. V. Nozhevnikova, I. A. Prokhorenko, V. A. Korshun, “Dianhydrides of 1(4)-substituted 7,8-diphenylbicyclo[2.2.2]oct-7-ene-2,3,5,6-tetracarboxylic acids”, Mendeleev Commun., 27:5 (2017), 446–447
Linking options:
https://www.mathnet.ru/eng/mendc2021
https://www.mathnet.ru/eng/mendc/v27/i5/p446
This publication is cited in the following 1 articles:
Barbara Herlah, Andrej Hoivik, Luka Jamšek, Katja Valjavec, Norio Yamamoto, Tyuji Hoshino, Krištof Kranjc, Andrej Perdih, “Design, Synthesis and Evaluation of Fused Bicyclo[2.2.2]octene as a Potential Core Scaffold for the Non-Covalent Inhibitors of SARS-CoV-2 3CLpro Main Protease”, Pharmaceuticals, 15:5 (2022), 539
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