aFaculty of Chemistry, University of Science, Vietnam National University, Hanoi, Hoan Kiem, Hanoi, Vietnam bInstitute of Biotechnology, Vietnam Academy of Science and Technology, Hanoi, Vietnam
Аннотация:
Two novel palladium(ii) complexes, trans-[PdBr2(tz-Mes)2] and trans-[PdBr2(tz-Dipp)2] featuring less explored 1,2,4-triazole-derived N-heterocyclic carbene (tz) have been synthesized. In solution, they exist both as trans-syn and trans-anti rotamers while their syn/anti ratios can be determined by 1H NMR harnessing the built-in aromatic rings as NMR probes. Complex trans-[PdBr2(tz-Mes)2] is highly cytotoxic toward A549, MCF-7, LNCaP and HT-29 cancerous cells.
Образец цитирования:
V.-H. Nguyen, H. T. Phung, D. T. Doan, T. T. Do, “Highly cytotoxic palladium(ii) complexes with 1,2,4-triazole-derived carbene ligands”, Mendeleev Commun., 32:5 (2022), 594–596
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc736
https://www.mathnet.ru/rus/mendc/v32/i5/p594
Эта публикация цитируется в следующих 3 статьяx:
L. S. Ermakova, V. S. Gracheva, O. A. Maiorova, M. V. Dmitriev, Yu. A. Beloglazova, V. A. Glushkov, “Synthesis and cytotoxic activity of PEPPSI complexes based on 2-R-5,6-dihydro[1,2,4]triazolo[3,4-a]isoquinolin-2-ium salts”, Russ Chem Bull, 73:4 (2024), 1072
M. S. Denisov, D. V. Eroshenko, “Synthesis of 2-nicotinylidene triterpenoids: structure, complexation with palladium, and in vitro cytotoxic activity”, Russ Chem Bull, 72:9 (2023), 2206
Diana V. Aleksanyan, Aleksandr V. Konovalov, Svetlana G. Churusova, Ekaterina Yu. Rybalkina, Alexander S. Peregudov, Svetlana A. Aksenova, Evgenii I. Gutsul, Zinaida S. Klemenkova, Vladimir A. Kozlov, “Modulation of the Cytotoxic Properties of Pd(II) Complexes Based on Functionalized Carboxamides Featuring Labile Phosphoryl Coordination Sites”, Pharmaceutics, 15:4 (2023), 1088
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