|
Эта публикация цитируется в 10 научных статьях (всего в 10 статьях)
Reactions of N-Aminoquinolones with Ketones: A New Approach to the Synthesis of Tricyclic 6-Fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acids
O. N. Chupakhina, Yu. A. Azevb, S. G. Alexeevc, S. V. Shorshnevb, E. Tsoid, V. N. Charushind
a I. Ya. Postovsky Institute of Organic Synthesis, Urals Branch of the Russian Academy of Sciences, Ekaterinburg, Russian Federation
b Ural Scientific Research Institute of Technology of Medical Preparations, Ekaterinburg, Russian Federation
c Urals State Technical University, Ekaterinburg, Russian Federation
d Department of Organic Chemistry, Urals State Technical University, Ekaterinburg, Russian Federation
Аннотация:
Reactions of 7-(X)-substituted ethyl 1-amino-4-oxo-1,4-dihydroquinoline-3-carboxylates (1a-c; X = F, Cl and 4-methylpiperazin-1-yl) with mono- and di-ketones have been studied. Treatment of 1a; X = F with cyclopentanone and cyclopentanone in acetic acid resulted in the corresponding azomethynes; α-dicarbonyl compounds such as glyoxal, glyoxylic acid or ethyl pyruvate caused desamination of 1a into ethyl, 6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate, while reactions of 1a-c with acetoacetone resulted in tricyclic 7-fluoro-4-oxopyrazolo[1,5-a]quinoline-4-carboxylic acids
Образец цитирования:
O. N. Chupakhin, Yu. A. Azev, S. G. Alexeev, S. V. Shorshnev, E. Tsoi, V. N. Charushin, “Reactions of N-Aminoquinolones with Ketones: A New Approach to the Synthesis of Tricyclic 6-Fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acids”, Mendeleev Commun., 2:4 (1992), 151–153
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc5451 https://www.mathnet.ru/rus/mendc/v2/i4/p151
|
| Статистика просмотров: |
| Страница аннотации: | 80 | | PDF полного текста: | 16 |
|
Обратная связь: