Аннотация:
A synthetic route to 1,4-benzothiazine-2-carboxylic acid 1,1 -dioxides, analogues of the ‘fluoroquinolone’ family of antibacterials, has been developed; unfortunately, the target compound (the thia-analogue of pefloxacin) has not revealed remarkable antibacterial activity in vitro against the majority of the strains tested.
Тип публикации:
Статья
Язык публикации: английский
Образец цитирования:
V. I. Vysokov, V. N. Charushin, G. B. Afanasyeva, O. N. Chupakhin, “The Synthesis of Fluorinated 4H-1,4-Benzothiazine-2-carboxylic Acid 1,1-Dioxides—Thionated Analogues of Pefloxacin”, Mendeleev Commun., 3:4 (1993), 159–160
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc5310
https://www.mathnet.ru/rus/mendc/v3/i4/p159
Эта публикация цитируется в следующих 8 статьяx:
Valery N. Charushin, Emiliya V. Nosova, Galina N. Lipunova, Oleg N. Chupakhin, Fluorine in Heterocyclic Chemistry Volume 2, 2014, 111
Kshamta Goyal, Naveen Gautam, Nishidha Khandelwal, D. C. Gautam, “Synthesis And Biological Activity Of Substituted 4H-1,4-Benzothiazines, Their Sulfones, And Ribofuranosides”, Nucleosides, Nucleotides and Nucleic Acids, 32:2 (2013), 81
Comprehensive Organic Name Reactions and Reagents, 2010, 2766
Mustafa M. El-Abadelah, Mohammed H. Al-Huniti, Jalal A. Zahra, Mustafa M. El-Abadelah, “Heterocycles [h]Fused on 4-Oxoquinoline-3-carboxylic Acid, II. A Facile Synthesis of Some 2,7-Dioxo[1,4]thiazin[2,3-h]quinoline-8-carboxylic Acids”, HETEROCYCLES, 71:2 (2007), 411
E. V. Nosova, N. N. Mochul'skaya, S. K. Kotovskaya, G. N. Lipunova, V. N. Charushin, “Fluorinated benzazoles and benzazines”, Heteroatom Chemistry, 17:6 (2006), 579
Vera L.de M. Guarda, Monique Perrissin, François Thomasson, Eulalia A. Ximenes, Suely L. Galdino, Ivan R. Pitta, Cuong Luu-Duc, Jacques Barbe, “Synthesis of 4-octyl-2H-1,4-benzo-thiazin-3-ones”, European Journal of Medicinal Chemistry, 38:7-8 (2003), 769
G. A. Mokrushina, V. N. Charushin, O. N. Chupakhin, “Relationship between structure and antibacterial activity in the fluoroquinolone series of compounds”, Pharm Chem J, 29:9 (1995), 590
V. I. VYSOKOV, V. N. CHARUSHIN, G. B. AFANASYEVA, O. N. CHUPAKHIN, “ChemInform Abstract: The Synthesis of Fluorinated 4H‐1,4‐Benzothiazine‐2‐carboxylic Acid 1, 1‐Dioxides ‐ Thionated Analogues of Pefloxacin.”, ChemInform, 25:34 (1994)
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