Эта публикация цитируется в 4 научных статьях (всего в 4 статьях)
Communications
Non-covalent conjugate based on graphene oxide and a cytotoxic agent containing 1,3,5-triazine derivative and (5-phenyl-2H-tetrazol-2-yl)acetoxy moiety: Synthesis, characterization, properties and cytotoxic activity
Аннотация:
The synthesis, identification and evaluation of the biological activity of a new non-covalent conjugate based on graphene oxide and (5-{[4,6-di(aziridin-1-yl)-1,3,5-triazin-2-yl]-amino}-2,2-dimethyl-1,3-dioxan-5-yl)methyl (5-phenyl-2H-tetrazol-2-yl)acetate were carried out. It was shown that the synthesized nanoconjugate is hemocompatible over the entire studied concentration range (10–100 μm) and demonstrates antiradical activity under irradiation. In addition, the conjugate exhibits cytotoxicity against A549 and HeLa cell lines with IC50 values of 4.0 and 73.7 μm, respectively.
Образец цитирования:
O. V. Mikolaichuk, O. S. Shemchuk, A. V. Protas, E. A. Popova, V. A. Ostrovskii, D. N. Maistrenko, O. E. Molchanov, V. V. Sharoyko, K. N. Semenov, “Non-covalent conjugate based on graphene oxide and a cytotoxic agent containing 1,3,5-triazine derivative and (5-phenyl-2H-tetrazol-2-yl)acetoxy moiety: Synthesis, characterization, properties and cytotoxic activity”, Mendeleev Commun., 33:6 (2023), 790–792
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc526
https://www.mathnet.ru/rus/mendc/v33/i6/p790
Эта публикация цитируется в следующих 4 статьяx:
O. S. Shemchuk, B. V. Paponov, D. A. Rakitianskii, D. N. Kalyuzhny, A. M. Rumyantsev, E. V. Sambuk, I. М. Bublik, P. V. Khomenko, P. A. Andoskin, O. E. Molchanov, D. N. Maistrenko, K. N. Semenov, V. V. Sharoyko, Mendeleev Commun., 35:1 (2025), 63–65
Konstantin N. Semenov, Olga S. Shemchuk, Boris V. Paponov, Gleb O. Iurev, Tatiana G. Grishacheva, Igor V. Murin, Dmitriy N. Maistrenko, Oleg E. Molchanov, Vladimir V. Sharoyko, “Cytotoxicity and photothermal properties of graphene oxide conjugate with folic acid and a cytostatic agent of styryl thiazolopyrimidinium class”, Fullerenes, Nanotubes and Carbon Nanostructures, 2024, 1
Konstantin N. Semenov, Olga S. Shemchuk, Olga V. Mikolaichuk, Igor V. Murin, Gleb O. Iurev, Sergei V. Ageev, Tatiana G. Grishacheva, Andrei M. Rumiantsev, Pavel A. Andoskin, Dmitrii N. Maistrenko, Oleg E. Molchanov, Vladimir V. Sharoyko, “Covalent conjugate based on graphene oxide and alkylating agent belonging to 1,3,5-triazine class as promising agent for anticancer chemo- and phototherapy”, Journal of Molecular Structure, 2024, 141046
O. V. Mikolaichuk, A. V. Protas, E. A. Popova, O. S. Shemchuk, M. D. Luttsev, D. R. Dadadzhanov, T. A. Vartanyan, A. V. Petrov, V. V. Sharoyko, K. N. Semenov, O. E. Molchanov, D. N. Maistrenko, “Synthesis, physicochemical properties and in vitro cytotoxic activity of aziridine-containing derivatives of 1,3,5-triazine”, Mendeleev Commun., 34:6 (2024), 859–861
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