Аннотация:
Compositions of doxorubicin with a terpolymer of N-vinylpyrrolidone, methacrylic acid and triethylene glycol dimethacrylate have been prepared and investigated by UV-VIS and NMR spectroscopy, cyclic voltammetry and DFT quantum chemical modeling. Oxygen containing groups of the terpolymer and hydrogen atoms of the drug OH and NH+ groups form hydrogen bonds. The compositions have lower cytotoxicity in vitro compared with that of free doxorubicin
Образец цитирования:
S. V. Kurmaz, I. I. Ivanova, N. S. Emelyanova, D. V. Konev, V. A. Kurmaz, N. V. Filatova, A. A. Balakina, A. A. Terentiev, “Doxorubicin compositions with biocompatible terpolymer of N-vinylpyrrolidone, methacrylic acid and triethylene glycol dimethacrylate”, Mendeleev Commun., 33:2 (2023), 255–258
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc367
https://www.mathnet.ru/rus/mendc/v33/i2/p255
Эта публикация цитируется в следующих 3 статьяx:
V. A. Kurmaz, D. V. Konev, S. V. Kurmaz, N. S. Emel'yanova, “Electrochemical Study of the Antitumor Antibiotic Doxorubicin in Its Free Form and Encapsulated in a Biocompatible Copolymer of N-Vinylpyrrolidone and (di)Methacrylates”, Russ J Electrochem, 60:4 (2024), 321
V. A. Kurmaz, D. V. Konev, S. V. Kurmaz, N. S. Emelyanova, “Electrochemical study of the free form of anti-tumor antibiotic doxorubicin and encapsulated in a biocompatible copolymer of N-vinyl pyrrolidone with (di)methacrylates”, Èlektrohimiâ, 60:4 (2024), 309
S. V. Kurmaz, I. V. Ulyanov, N. S. Emelyanova, V. A. Kurmaz, A. V. Kozlov, L. R. Sizov, A. Yu. Rybkin, “Nanosized systems of aluminum phthalocyanine and amphiphilic copolymers of N-vinylpyrrolidone with mono- and dimethacrylates for photodynamic therapy and fluorescence diagnostics”, Mendeleev Commun., 34:4 (2024), 492–495