Аннотация:
Novel purine and 2-aminopurine conjugates containing fragments of (S)-aspartic and (S)-glutamic acids with free α-functional groups attached via a 1,2-ethylenediamine linker at 6-position of the purine core, as well as their analogues with N9-(2-hydroxyethoxy)methyl substituent have been synthesized. Among the conjugates obtained, compounds exhibiting a significant antimycobacterial activity have been found.
Образец цитирования:
D. A. Gruzdev, E. N. Chulakov, G. L. Levit, M. A. Kravchenko, V. P. Krasnov, V. N. Charushin, “Synthesis and antimycobacterial activity of novel purin-6-yl and 2-aminopurin-6-yl conjugates with (S)-aspartic and (S)-glutamic acids”, Mendeleev Commun., 27:6 (2017), 547–549
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc2054
https://www.mathnet.ru/rus/mendc/v27/i6/p547
Эта публикация цитируется в следующих 15 статьяx:
A. Yu. Vigorov, E. B. Gorbunov, M. A. Ezhikova, M. I. Kodess, D. V. Belyaev, D. V. Vakhrusheva, G. L. Levit, V. P. Krasnov, “Synthesis of purine conjugates with N-(4-aminobenzenesulfonyl)-and N-(2-aminoethanesulfonyl)-(S)-glutamic acids”, Russ Chem Bull, 71:12 (2022), 2685
A. A. Telegina, D. A. Gruzdev, G. L. Levit, V. P. Krasnov, “Synthesis of new conjugates of 6-thiopurine and thioguanine with (S)-glutamic acid”, Russ Chem Bull, 71:11 (2022), 2426
Vera V. Musiyak, Irina A. Nizova, Evgeny N. Chulakov, Liliya Sh. Sadretdinova, Andrey A. Tumashov, Galina L. Levit, Victor P. Krasnov, “Stereochemical aspects in the synthesis of novel N-(purin-6-yl)dipeptides as potential antimycobacterial agents”, Amino Acids, 53:3 (2021), 407
Olga А. Vozdvizhenskaya, Valeriya L. Andronova, Georgii А. Galegov, Galina L. Levit, Victor P. Krasnov, Valery N. Charushin, “Synthesis and antiherpetic activity of novel purine conjugates with 7,8-difluoro-3-methyl-3,4-dihydro-2H-1,4-benzoxazine”, Chem Heterocycl Comp, 57:4 (2021), 490
Angel García-Raso, Angel Terrón, Joaquín Ortega-Castro, Miquel Barceló-Oliver, Julia Lorenzo, Sergi Rodríguez-Calado, Antonio Franconetti, Antonio Frontera, Ezequiel M. Vázquez-López, Juan J. Fiol, “Iridium(III) coordination of N(6) modified adenine derivatives with aminoacid chains”, Journal of Inorganic Biochemistry, 205 (2020), 111000
Victor P. Krasnov, Galina L. Levit, Vera V. Musiyak, Dmitry A. Gruzdev, Valery N. Charushin, “Fragment-based approach to novel bioactive purine derivatives”, Pure and Applied Chemistry, 92:8 (2020), 1277
Sh. M. Salikhov, R. R. Zaripov, I. B. Abdrakhmanov, “Intramolecular Heterocyclization of o-(1-Cycloalkenyl)anilines: III. Synthesis of Optically Active
4H-3,1-Benzoxazines Based on α-Amino
Acids”, Russ J Org Chem, 56:9 (2020), 1613
Angel García-Raso, Angel Terrón, Bartomeu Balle, Adela López-Zafra, Antonio Frontera, Miquel Barceló-Oliver, Juan J. Fiol, “Crystal structures of N6-modified-amino acid nucleobase analogs(iii): adenine–valeric acid, adenine–hexanoic acid and adenine–gabapentine”, New J. Chem., 44:28 (2020), 12236
V. V. Musiyak, I. A. Nizova, T. V. Matveeva, G. L. Levit, V. P. Krasnov, V. N. Charushin, “Synthesis of New Purine Derivatives Containing α- and ω-Amino Acid Fragments”, Russ J Org Chem, 55:6 (2019), 762
Angel García-Raso, Angel Terrón, Adela López-Zafra, Andrés García-Viada, Agostina Barta, Antonio Frontera, Julia Lorenzo, Sergi Rodríguez-Calado, Ezequiel M. Vázquez-López, Juan J. Fiol, “Crystal structures of N6-modified-amino acid related nucleobase analogs (II): hybrid adenine-β-alanine and adenine-GABA molecules”, New J. Chem., 43:24 (2019), 9680
D. Liang, Yu. Wang, “The first synthesis of 7-prenylisatin”, Mendeleev Commun., 29:2 (2019), 172–173
V. V. Musiyak, D. A. Gruzdev, M. A. Kravchenko, D. V. Vakhrusheva, G. L. Levit, V. P. Krasnov, V. N. Charushin, “Synthesis and antimycobacterial activity of purine conjugates with (S)-lysine and (S)-ornithine”, Mendeleev Commun., 29:1 (2019), 11–13
A. A. Tumashov, D. A. Gruzdev, A. Yu. Vigorov, V. V. Musiyak, E. N. Chulakov, G. L. Levit, V. P. Krasnov, V. N. Charushin, “Analysis of racemic conjugates of purine with heterocyclic amines by chiral high-performance liquid chromatography”, Russ Chem Bull, 67:9 (2018), 1704
Angel García-Raso, Angel Terrón, Antonio Bauzá, Antonio Frontera, Jhon J. Molina, Ezequiel M. Vázquez-López, Juan J. Fiol, “Crystal structures of N6-modified-aminoacid/peptide nucleobase analogs: hybrid adenine–glycine and adenine–glycylglycine molecules”, New J. Chem., 42:18 (2018), 14742
Д. А. Груздев, В. В. Мусияк, Г. Л. Левит, В. П. Краснов, В. Н. Чарушин, “Производные пурина, обладающие противотуберкулезной активностью”, Усп. хим., 87:6 (2018), 604–618; D. A. Gruzdev, V. V. Musiyak, G. L. Levit, V. P. Krasnov, V. N. Charushin, “Purine derivatives with antituberculosis activity”, Russian Chem. Reviews, 87:6 (2018), 604–618
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