Аннотация:
For the development of new antitumor agents, novel dibenzo-1,7-diaza-14-crown-4 ethers containing γ-piperidone moiety were synthesized by a domino condensation of new podands, ketones and ammonium acetate. The crystal structure of one Ts of them was studied by X-ray diffraction. Four crown compounds were evaluated in vitro for cytotoxic activity against 5 human cancer cell lines.
Образец цитирования:
A. T. Le, V. T. Tran, H. H. Truong, L. M. Nguyen, D. M. Luong, T. T. Do, D. T. Nguyen, N. T. Dao, D. T. Le, A. T. Soldatenkov, V. N. Khrustalev, “Synthesis and cytotoxicity of novel γ-piperidone-containing dibenzo-1,7-diaza-14-crown-4 ethers”, Mendeleev Commun., 29:4 (2019), 375–377
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc1527
https://www.mathnet.ru/rus/mendc/v29/i4/p375
Эта публикация цитируется в следующих 13 статьяx:
Nguyen Tien Dat, Tran Thi Thanh Van, Dao Thi Nhung, Cao Quoc Anh, Tran Thanh Hang, Vu Thi Thao, Victor Khrustalev, Le Tuan Anh, “Trithiazacrown Ethers Containing Piperidine Heterocycle: Synthesis, Structural Characterization and Evaluation Of α‐Glucosidase Inhibitory Activity”, ChemistrySelect, 9:3 (2024)
Dao T. Nhung, Nguyen N. Tram, Pham T. T. Tam, Kseniia A. Alekseeva, Victor N. Khrustalev, Dang T. Hoang, Le. T. Duan, Le. T. Anh, “Synthesis, α‐Glucosidase Inhibitory Activity, and Molecular Docking Studies of Tri(benzo)‐5‐azacrownophanes with a γ‐Piperidone Moiety”, ChemistrySelect, 8:25 (2023)
D. T. Nguyen, H. H. Truong, N. T. Dao, V. T. Tran, O. S. Gorchakova, A. T. Le, “Unexpected hydrazine- and hydroxylamine-induced transformations of aza-14-crown-4 incorporating 4-oxopiperidine-3-carboxylate moiety”, Mendeleev Commun., 33:5 (2023), 708–710
N. T. Dao, T. T. Do, T. T. Pham, V. T. Tran, V. N. Khrustalev, A. T. Le, “Molecular structure and ultrasound-assisted synthesis of the diazacrown derivative containing 2,3,4,6-tetraaryl-γ piperidone”, Mendeleev Commun., 33:5 (2023), 711–713
Tung H. To, Dang B. Tran, Thang C. Pham, Phong D. Tran, “A new approach to pyrimidine-type heterocycles based on Petrenko–Kritschenko synthesis”, Chem Heterocycl Comp, 58:11 (2022), 608
Nhung T. Dao, Victor N. Khrustalev, Elena I. Polyakova, Anh T. Le, “Synthesis and Biological Evaluation of Azacrownophanes Containing Tetrahydropyridine or Piperidone Subunits”, ChemistrySelect, 7:48 (2022)
S. A. Rzhevskiy, M. A. Topchiy, V. N. Bogachev, L. I. Minaeva, I. R. Cherkashchenko, K. V. Lavrov, G. K. Sterligov, M. S. Nechaev, A. F. Asachenko, “Solvent-free palladium-catalyzed C–O cross-coupling of (hetero)aryl halides with primary alcohols”, Mendeleev Commun., 32:2 (2022), 258–259
N. T. Dao, D. T. Nguyen, L. M. Nguyen, V. T. T. Tran, T. T. Do, A. T. Le, “Synthesis of Dithiacrown Ethers and Evaluation of Their Cytotoxic Activity”, ChemistrySelect, 6:40 (2021), 11081
Thanh Van Tran Thi, Manh Linh Nguyen, Tien Dat Nguyen, The Duan Le, Hong Hieu Truong, Victor N. Khrustalev, Tuan Anh Le, “Synthesis of the First Dithiaaza-17-Crown-5 Ethers Containing Piperidin-4-One Subunit”, Chem Heterocycl Comp, 57:10 (2021), 1057
Ayalew T. Wodajo, Thi Thanh Van Tran, Hong Hieu Truong, Alexander G. Tskhovrebov, The Duan Le, Victor N. Khrustalev, Tuan Anh Le, “Synthesis by deamination reaction and crystal structure at 120 K of (16Z,19E)-18-oxo-N-(pyridin-2-yl)-6,7,9,10-tetrahydro-18H-dibenzo[h,o][1,4,7]trioxacyclohexadecine-17-carboxamide”, Acta Crystallogr E Cryst Commun, 76:9 (2020), 1454
L. M. Nguyen, H. H. Truong, V. N. Khrustalev, S. T. Truong, D. T. Nguyen, V. T. Tran, S. T. Mai, V. T. Tran, A. T. Le, “Synthesis and biological evaluation of novel phane-structured diazacrowns containing γ-piperidone and pyridine rings”, Mendeleev Commun., 30:6 (2020), 753–755
А. Д. Зубенко, О. А. Фёдорова, “Ароматические и гетероароматические азакраун-соединения: преимущества и недостатки жестких макроциклических лигандов”, Усп. хим., 89:7 (2020), 750–786; A. D. Zubenko, O. A. Fedorova, “Aromatic and heteroaromatic azacrown compounds: advantages and disadvantages of rigid macrocyclic ligands”, Russian Chem. Reviews, 89:7 (2020), 750–786
A. T. Le, N. T. Dao, H. H. Truong, T. T. Do, E. I. Polyakova, I. V. Lin'ko, P. V. Dorovatovskii, V. N. Khrustalev, “Unexpected formation of dinaphthoaza-17-crown-5 ether containing γ-aminopiperidine subunit”, Mendeleev Commun., 29:6 (2019), 698–699