Synthesis and biological activity of thiazole–carbohydrate conjugates based on thiacarpine, an analogue of the cytotoxic alkaloid from the ascidian Polycarpa aurata
Аннотация:
Based on bis(2-amino-4-phenyl-5-thiazolyl) disulfides, thiazole analogues of polycarpine, a cytotoxic alkaloid from the ascidian Polycarpa aurata, a wide range of thiazole–carbohydrate conjugates based on D-glucose and D-xylose has been obtained. Antitumor and antimicrobial activity for the synthesized compounds has been studied.
Образец цитирования:
D. N. Pelageev, S. M. Kovach, N. N. Balaneva, Yu. E. Sabutski, K. L. Borisova, E. S. Menchinskaya, E. A. Chingizova, A. R. Chingizov, A. L. Burylova, O. Yu. Slabko, K. A. Drozdov, V. Ph. Anufriev, “Synthesis and biological activity of thiazole–carbohydrate conjugates based on thiacarpine, an analogue of the cytotoxic alkaloid from the ascidian Polycarpa aurata”, Mendeleev Commun., 35:1 (2025), 66–68