Аннотация:
A three-component tandem protocol involving the reactions of bis(benzohydrazides), aromatic aldehydes and chloramine trihydrate yielded a new series of bis(1,3,4-oxadiazoles). The target hybrids were formed by an initial bis(N-benzoyl-hydrazones) formation, followed by chloramine trihydrate- mediated oxidative cyclization. The 4-methoxyphenyl-containing compounds demonstrated promising antibacterial activity against the Staphylococcus aureus and Pseudomonas aeruginosa strains with MIC value of 1.6 µm.
Образец цитирования:
A. E. Mekky, Sh. M. Sanad, A. M. Abdelfattah, “Tandem synthesis, antibacterial evaluation and SwissADME prediction study of new bis(1,3,4-oxadiazoles) linked to arene units”, Mendeleev Commun., 32:5 (2022), 612–614
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc742
https://www.mathnet.ru/rus/mendc/v32/i5/p612
Эта публикация цитируется в следующих 18 статьяx:
E. A. Gerasimova, D. M. Egorov, “Synthesis of Phosphonylated 5-Alkyl-1,3,4-oxadiazoles Based on Dialkyl Chloroethynylphosphonates”, Russ J Gen Chem, 94:8 (2024), 1941
Ahmed E. M. Mekky, Sherif M. H. Sanad, “New Bis(pyrazolo[5,1‐b]quinazolines) and Bis(9H‐xanthenediones) Linked to Alkane Cores: One‐Pot Synthesis, Antibacterial Screening, and SAR Study”, Chemistry & Biodiversity, 2024
Mohamed A. A. Elneairy, Emad G. N. Youssef, Sama A. A. Ebrahim, Nour E. M. Mohammad, Nourhan M. S. Abd El‐Rahman, Ahmed S. M. Elhewaty, Sherif M. H. Sanad, Ahmed E. M. Mekky, “MRSA Inhibitory Activity of Some New Pyrazolo[1,5‐a]pyrimidines Linked to Arene and/or Furan or Thiophene Units”, Chemistry & Biodiversity, 2024
L. V. Vinogradova, K. Yu. Komarova, M. V. Chudinov, E. V. Rogacheva, L. A. Kraeva, A. Yu. Lukin, “Scaffold hopping in the oxadiazole antibiotic structure leads to more active compounds”, Mendeleev Commun., 34:3 (2024), 362–364
Sherif M. H. Sanad, Ahmed E. M. Mekky, “Tandem synthesis and antibacterial screening of new thieno[2,3-b]pyridine-fused pyrimidin-4(3H)-ones linked to thiazole or oxazole units”, Synthetic Communications, 53:13 (2023), 994
Zeinab A. Abdallah, Sherif M. H. Sanad, Ahmed E. M. Mekky, Mohamed S. Mohamed Ahmed, “New Arylazo‐Based (Chromene‐Thiazole) Hybrids as Potential MRSA Inhibitors”, Chemistry & Biodiversity, 20:4 (2023)
Sherif M. H. Sanad, Ahmed E. M. Mekky, “Three-component regioselective synthesis and antibacterial evaluation of new arene-linked bis(pyrazolo[1,5-a]pyrimidine) hybrids”, Synthetic Communications, 53:9 (2023), 658
Maria Lopez-Ramos, Lauro Figueroa-Valverde, Francisco Diaz-Cedillo, Marcela Rosas-Nexticapa, Magdalena Alvarez-Ramirez, “Theoretical Evaluation of Twenty-Cannabinoid Derivatives on Either Androgen Receptor or 5α-Reductase Enzyme”, Clin Cancer Investig J, 12:2 (2023), 27
Sherif M. H. Sanad, Alshimaa A. M. Abdelsalam, Aya A. Gamal Eldin, Esraa H. Abdelfattah, Fatma R. M. Hussein, Nada G. Mohammed, Nariman A. S. Taha, Ahmed E. M. Mekky, “Synthesis of New Bis(pyrazolo[1,5‐a]pyrimidines) Linked to Different Spacers as Potential MurB Inhibitors”, Chemistry & Biodiversity, 20:6 (2023)
Lauro Figueroa-Valverde, López-Ramos Maria, Alvarez-Ramirez Magdalena, Rosas Nexticapa Marcela, Díaz-Cedillo Francisco, Mateu-Armad Maria Virginia, Lopez-Gutierrez Tomas, “Evaluation of coumarin and their derivatives as Janus Kinase-3 inhibitors using a theoretical model”, Braz. J. of Sci., 2:12 (2023), 106
Ahmed E. M. Mekky, Nariman A. S. Taha, Nada G. Mohammed, Fatma R. M. Hussein, Esraa H. Abdelfattah, Aya A. Gamal Eldin, Alshimaa A. M. Abdelsalam, Sherif M. H. Sanad, “Development of pyrazolo[1,5-a]pyrimidine-based antibacterial agents”, Synthetic Communications, 53:13 (2023), 1053
Ahmed E. M. Mekky, Sherif M. H. Sanad, “[3+2] cycloaddition synthesis of new (nicotinonitrile‐chromene)‐based bis(pyrazole) hybrids as potential acetylcholinesterase inhibitors”, Journal of Heterocyclic Chem, 60:1 (2023), 156
Mohamed A. A. Elneairy, Sherif M. H. Sanad, Ahmed E. M. Mekky, “One-pot synthesis and antibacterial screening of new (nicotinonitrile-thiazole)-based mono- and bis(Schiff bases) linked to arene units”, Synthetic Communications, 53:3 (2023), 245
Maria Lopez-Ramos, Lauro Figueroa-Valverde, Marcela Rosas-Nexicapa, Catalina Cervantes-Ortega, Magdalena Alvarez-Ramirez, Francisco Diaz-Cedillo, Maria Virginia Mateu-Armand, Tomas Lopez-Gutierrez, “Interaction of benzenesulfonamide derivatives with Smyd3 using a theoretical model”, Braz. J. of Sci., 3:1 (2023), 115
A. E. Mekky, Sh. M. Sanad, “Antibacterial screening of new bis(pyrazolo[1,5-a]pyrimidine) hybrids linked to different spacers”, Mendeleev Commun., 33:3 (2023), 331–333
Ahmed E. M. Mekky, Sherif M. H. Sanad, “Microwave-assisted synthesis of nicotinonitrile and/or arene-linked bis(chromene-thiazoles) as new VRE and MRSA inhibitors”, Synthetic Communications, 52:24 (2022), 2276
Ahmed E. M. Mekky, Sherif M. H. Sanad, “New thiazole-based bis(Schiff bases) linked to arene units as potential MRSA inhibitors”, Synthetic Communications, 52:23 (2022), 2205
Sherif M. H. Sanad, Ahmed E. M. Mekky, “Ultrasound‐Mediated Synthesis of New (Piperazine‐Chromene)‐Linked Bis(thieno[2,3‐b]pyridine) Hybrids as Potential Anti‐acetylcholinesterase”, ChemistrySelect, 7:41 (2022)
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