Аннотация:
A simple and efficient synthesis of 2-RF-pyrimido[1,2-a]benzimidazole-4-carbaldehyde derivatives comprises the reaction between 3-(polyfluoroacetyl)pyruvaldehyde dimethyl acetals and 2-aminobenzimidazole. The effects of fluorinated substituents in 3-(polyfluoroacetyl)pyruvaldehyde dimethyl acetals and the reaction conditions on regiochemical outcome of this reaction have been estimated.
Образец цитирования:
D. V. Belyaev, D. L. Chizhov, M. I. Kodess, M. A. Ezhikova, G. L. Rusinov, V. N. Charushin, “Synthesis of 2-(polyfluoromethyl)pyrimido-[1,2-a]benzimidazole-4-carbaldehyde derivatives”, Mendeleev Commun., 29:3 (2019), 249–251
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc1485
https://www.mathnet.ru/rus/mendc/v29/i3/p249
Эта публикация цитируется в следующих 5 статьяx:
Yu. O. Edilova, E. A. Osipova, Yu. S. Kudyakova, P. A. Slepukhin, V. I. Saloutin, D. N. Bazhin, “Polyfunctionalized pyrimidines based on 1,2,4-triketones”, Russ Chem Bull, 73:7 (2024), 1968
Satyanarayana Gadde, Ane Kleynhans, Jessica K. Holien, Mohan Bhadbhade, Phuoc Linh Dan Nguyen, Ritu Mittra, Tsz Tin Yu, Daniel R. Carter, Michael W. Parker, Glenn M. Marshall, Belamy B. Cheung, Naresh Kumar, “Pyrimido[1,2-a]benzimidazoles as inhibitors of oncoproteins ubiquitin specific protease 5 and MYCN in the childhood cancer neuroblastoma”, Bioorganic Chemistry, 136 (2023), 106462
D. N. Bazhin, Yu. S. Kudyakova, Yu. O. Edilova, Ya. V. Burgart, V. I. Saloutin, “Fluorinated 1,2,4-triketone analogs: new prospects for heterocyclic and coordination chemistry”, Russ Chem Bull, 71:7 (2022), 1321
Victor V. Fedotov, Vladimir L. Rusinov, Evgeny N. Ulomsky, Evgeny M. Mukhin, Evgeny B. Gorbunov, Oleg N. Chupakhin, “Pyrimido[1,2-a]benzimidazoles: synthesis and perspective of their pharmacological use”, Chem Heterocycl Comp, 57:4 (2021), 383
Vitaly А. Osyanin, Dmitry V. Osipov, Kirill S. Korzhenko, Oleg P. Demidov, Yuri N. Klimochkin, “4H-Chromenes as 1,3-bielectrophiles in the reaction with 2-aminobenzimidazole: synthesis of pyrimido[1,2-a]benzimidazoles”, Chem Heterocycl Comp, 57:5 (2021), 588
Обратная связь: