A novel thermoresponsive polypeptide: synthesis and characterization

Polypeptide consisting of ψ-N-isopropyl glutamine and glutamic acid (90 : 10, mol/mol) was synthesized by post- polymerization modification of poly(ψ-methyl glutamate). The obtained polypeptide exhibited thermoresponsive properties with the lowest critical solution temperature in the range of 41–54 °C depending on the medium and polymer concentration.