Abstract:
Mechanisms of interaction between nucleic acid molecules and magnetic nanoparticles and methods of their conjugation in order to develop functional nanostructures are considered. The properties of nucleic acids and magnetic nanoparticles that are key to the design of nanobiocomposites are described. Prospects for applications of nanobiocomposites in nanoelectronics and medicine are analyzed. Possible harmful effects of magnetic nanoparticles on the genetic system are briefly outlined. The bibliography includes 287 references.
Received: 21.05.2013
Bibliographic databases:
Language: English
Original paper language: Russian
Citation:
A. G. Pershina, A. E. Sazonov, V. D. Filimonov, “Magnetic nanoparticles–DNA interactions: design and applications of nanobiohybrid systems”, Russian Chem. Reviews, 83:4 (2014), 299–322