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Mendeleev Communications, 2022, Volume 32, Issue 5, Pages 606–608
DOI: https://doi.org/10.1016/j.mencom.2022.09.012 (Mi mendc740) 		 
This article is cited in 1 scientific paper (total in 1 paper)

Communications

Novel naphthalene-based bis-pyridinium compounds with pronounced antibacterial activity

N. A. Frolova, V. A. Smirnovab, E. V. Detushevac, A. N. Vereshchagina

a N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
b D.Mendeleev University of Chemical Technology of Russia, Moscow, Russian Federation
c State Research Center for Applied Microbiology & Biotechnology, Obolensk, Moscow Region, Russian Federation
Full-text PDF (175 kB) Citations (1)
DOI: https://doi.org/10.1016/j.mencom.2022.09.012
Abstract: Novel para-substituted bis-pyridinium compounds containing 2,7-dioxynaphthalene spacer were synthesized in two simple steps from the corresponding dihydroxy-naphthalene. The microbiological study on five reference (E. coli ATCC 25922, K. pneumoniae ATCC 70060, S. aureus ATCC 43300, P. aeruginosa ATCC27853, and A. baumannii ATCC 15308) and five clinical (E. coli B-3421/19,K. pneumoniae B-2523/18, S. aureus B-8648, P. aeruginosa B-2099/18 and A. baumannii B-2926/18) bacterial strains showed promising range of antibacterial properties for these biocides, compared to modern sanitizers.
Keywords: quaternary bis-ammonium compounds, pyridinium compounds, alkylation, biological activity, antibacterial agents, biocides.
Document Type: Article
Language: English
Supplementary materials:
Supplementary_data_1.pdf (2.0 Mb)


Citation: N. A. Frolov, V. A. Smirnov, E. V. Detusheva, A. N. Vereshchagin, “Novel naphthalene-based bis-pyridinium compounds with pronounced antibacterial activity”, Mendeleev Commun., 32:5 (2022), 606–608
Linking options:
  • https://www.mathnet.ru/eng/mendc740
  • https://www.mathnet.ru/eng/mendc/v32/i5/p606
    • This publication is cited in the following 1 articles:
    1. Nikita A. Frolov, Mary A. Seferyan, Elena V. Detusheva, Elizabeth Son, Ilya G. Kolmakov, Alena S. Kartseva, Victoria V. Firstova, Anatoly N. Vereshchagin, Michail N. Elinson, “Development of Naphthalene-Derivative Bis-QACs as Potent Antimicrobials: Unraveling Structure–Activity Relationship and Microbiological Properties”, Molecules, 29:23 (2024), 5526  crossref
    Citing articles in Google Scholar: Russian citations, English citations
    Related articles in Google Scholar: Russian articles, English articles
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