Loading [MathJax]/jax/output/SVG/config.js
Mendeleev Communications
RUS  ENG    JOURNALS   PEOPLE   ORGANISATIONS   CONFERENCES   SEMINARS   VIDEO LIBRARY   PACKAGE AMSBIB  
General information
Latest issue
Archive

Search papers
Search references

RSS
Latest issue
Current issues
Archive issues
What is RSS


Mendeleev Commun.:
Year:
Volume:
Issue:
Page:
Find




Personal entry:
Login:
Password:
Save password
Enter
Forgotten password?
Register

Mendeleev Communications, 2022, Volume 32, Issue 2, Pages 183–185
DOI: https://doi.org/10.1016/j.mencom.2022.03.010 (Mi mendc607) 		 
This article is cited in 4 scientific papers (total in 4 papers)

Communications

Cytotoxicity of novel cross-conjugated arylated cyclopentene-1,3-diones

V. A. Egorova, L. S. Khasanovaa, F. A. Gimalovaa, A. N. Lobova, D. V. Ishmetovab, V. A. Vakhitovb, M. S. Miftakhova

a Ufa Institute of Chemistry, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russian Federation
b Institute of Biochemistry and Genetics, Ufa Federal Research Center of the Russian Academy of Sciences, Ufa, Russian Federation
Full-text PDF (166 kB) Citations (4)
DOI: https://doi.org/10.1016/j.mencom.2022.03.010
Abstract: Novel 2,4-dichloro-5-phenylcyclopent-4-ene-1,3-dione and 5-aryl-4-chlorocyclopent-4-ene-1,3-dione were synthesized by the Suzuki–Miyaura or Friedel–Crafts reactions of the di- and trichlorocyclopentenone monoketals and subsequent hydrolysis of the ketal function. Condensation of these diones with (hetero)aromatic aldehydes afforded multifunctional 1,3-cyclopentenediones that showed anticancer activity.Keywords: organochlorine compounds, cyclopentenones, ketals, Suzuki–Miyaura reaction, Friedel–Crafts reaction, Knoevenagel condensation, aldehydes, cross-conjugated cyclopentene-1,3-diones, cytotoxicity.
Keywords: organochlorine compounds, cyclopentenones, ketals, Suzuki–Miyaura reaction, Friedel–Crafts reaction, Knoevenagel condensation, aldehydes, cross-conjugated cyclopentene-1, 3-diones, cytotoxicity.
Document Type: Article
Language: English
Supplementary materials:
Supplementary_data_1.pdf (1.5 Mb)


Citation: V. A. Egorov, L. S. Khasanova, F. A. Gimalova, A. N. Lobov, D. V. Ishmetova, V. A. Vakhitov, M. S. Miftakhov, “Cytotoxicity of novel cross-conjugated arylated cyclopentene-1,3-diones”, Mendeleev Commun., 32:2 (2022), 183–185
Linking options:
  • https://www.mathnet.ru/eng/mendc607
  • https://www.mathnet.ru/eng/mendc/v32/i2/p183
    • This publication is cited in the following 4 articles:
    1. V. A. Egorov, L. S. Khasanova, F. A. Gimalova, M. S. Miftakhov, “Double Acylation Product in the SnCl4-promoted Reaction of 4,5-Dichlorocyclopent-4-en-1,3-dione with 1,3,5-Trimethoxybenzene”, Russ J Org Chem, 59:8 (2023), 1449  crossref
    2. V. A. Egorov, L. S. Khasanova, F. A. Gimalova, M. S. Miftakhov, “Double acylation product in the snsl<sub>4</sub>-promoted reaction of 4,5-dichlorocyclopent-4-en-1,3-dione with 1,3,5-trimethoxybenzene”, Žurnal organičeskoj himii, 59:8 (2023), 1096  crossref
    3. A. F. Schmidt, A. A. Kurokhtina, E. V. Larina, N. A. Lagoda, S. A. Gurevich, D. A. Yavsin, I. N. Krotova, V. M. Zelikman, T. N. Rostovshchikova, I. G. Tarkhanova, “Advanced heterogeneous Pd catalysts for the Suzuki–Miyaura reaction with aryl bromides”, Mendeleev Commun., 33:2 (2023), 177–179  mathnet  crossref
    4. V. A. Egorov, L. S. Khasanova, F. A. Gimalova, D. V. Ishmetova, M. S. Miftakhov, “Zinc-promoted Reactions of (2Z,E)-[2-Aryl(hetaryl)methylidene]-4-chloro-5-phenyl(2,4,6-trimethoxyphenyl)cyclopent-4-ene-1,3-diones with Methyl Bromoacetate”, Russ J Org Chem, 58:11 (2022), 1668  crossref
    Citing articles in Google Scholar: Russian citations, English citations
    Related articles in Google Scholar: Russian articles, English articles
    		Mendeleev Communications
    Statistics & downloads:
    Abstract page:31
    Full-text PDF :7
     
      Contact us:
    math-net2025_03@mi-ras.ru     		 Terms of Use  Registration to the website  Logotypes © Steklov Mathematical Institute RAS, 2025