Abstract:
Hexa-O-acetyl-D-gentiobial 1 and its decyclization product (2E,4S,5R)-4-acetoxy-5-hydroxy-6-(2,3,4,6-tetra-O-acetyl-β-D-gluco-pyranosyloxy)hex-2-enal 2 have been used to synthesize O-glycosylated aminodiols 9, 10, 15 that model the structure of natural lysocerebrosides. Compounds 9, 10, 15 can serve as basic components to produce N-acylated conjugates with derivatives of arachidonic and glycyrrhizic acids.
Document Type:
Article
Language: English
Citation:
A. G. Tolstikov, O. V. Tolstikova, G. A. Tolstikov, “Hexa-O-acetyl-D-gentiobial in enantioselective synthesis of lysocerebrosides and their conjugates”, Mendeleev Commun., 6:4 (1996), 128–130
Linking options:
https://www.mathnet.ru/eng/mendc4945
https://www.mathnet.ru/eng/mendc/v6/i4/p128
This publication is cited in the following 2 articles:
A. G. Tolstikov, G. A. Tolstikov, “Unsaturated sugars in enantiospecific synthesis of natural low-molecular bioregulators and their structural analogues”, Russ J Bioorg Chem, 33:1 (2007), 3
A. G. TOLSTIKOV, O. V. TOLSTIKOVA, G. A. TOLSTIKOV, “ChemInform Abstract: Hexa‐O‐acetyl‐D‐gentiobial in Enantioselective Synthesis of Lysocerebrosides and Their Conjugates.”, ChemInform, 27:46 (1996)
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