Abstract:
The synthesis of 20-azido(tri-n-butyltin)benzoate of 20-hydroxy-(8S)-hepoxilin A3 (HxA3‡‡Trivial names and abbreviations: HxA3: 11(S),12(S)-epoxy-8(R)- and 8(S)-hydroxyeicosa-5(Z),9(E),14(Z)-trienoic acids; HxB3: 11(S),12(S)-epoxy-10(R)- and 10(S)-hydroxyeicosa-5(Z),8(Z),14(Z)-trienoic acids.) methyl ester, a tool for the labeling of proteins involved in hepoxilin metabolism, has been performed starting from a synthetic precursor of 20-hydroxy hepoxilins.
Document Type:
Article
Language: English
Citation:
P. M. Demin, D. M. Kochev, H. Perrier, C. R. Pace-Asciak, K. K. Pivnitsky, “Synthesis of a photoaffinic hepoxilin analog”, Mendeleev Commun., 7:3 (1997), 90–91
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https://www.mathnet.ru/eng/mendc/v7/i3/p90
This publication is cited in the following 4 articles:
Cecil R. Pace-Asciak, “Pathophysiology of the hepoxilins”, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1851:4 (2015), 383
Cecil R. Pace-Asciak, “Hepoxilins in cancer and inflammation—use of hepoxilin antagonists”, Cancer Metastasis Rev, 30:3-4 (2011), 493
Seongjin Kim, Yurdanur Adiyaman, Goutam Saha, William S Powell, Joshua Rokach, “A photoaffinity probe for 5-hydroxyeicosanoid dehydrogenase suitable for radioiodination”, Tetrahedron Letters, 42:27 (2001), 4445
V. I. Mel'nikova, L. L. Vasil'eva, K. K. Pivnitsky, “Synthetic research on hepoxilins”, Russ Chem Bull, 47:6 (1998), 1199
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