Abstract:
The reaction of N-(ethoxycarbonyl)methyl substituted ethyl 6,7-difluoro-, 6,7,8-trifluoro- and 5,6,7,8-tetrafluoro-4-oxo-1,4-dihydroquinoline-3-carboxylates with methyl methacrylate results in the [3 + 2] adducts, hexahydropyrrolo[1,2-a]quinolones, which can be precursors of [a]-fused fluoroquinolones.
Document Type:
Article
Language: English
Citation:
E. Tsoi, V. N. Charushin, E. V. Nosova, G. N. Lipunova, A. V. Tkachev, “New approach to [a]-fused fluoroquinolones: the synthesis of 5-oxo-1,2,3,3a,4,5-hexahydropyrrolo[1,2-a]quinolines”, Mendeleev Commun., 11:2 (2001), 53–54
Linking options:
https://www.mathnet.ru/eng/mendc4213
https://www.mathnet.ru/eng/mendc/v11/i2/p53
This publication is cited in the following 5 articles:
L. V. Politanskaya, G. A. Selivanova, E. V. Panteleeva, E. V. Tretyakov, V. E. Platonov, P. V. Nikul'shin, A. S. Vinogradov, Ya. V. Zonov, V. M. Karpov, T. V. Mezhenkova, A. V. Vasilyev, A. B. Koldobskii, O. S. Shilova, S. M. Morozova, Ya. V. Burgart, E. V. Shchegolkov, V. I. Saloutin, V. B. Sokolov, A. Yu. Aksinenko, V. G. Nenajdenko, M. Yu. Moskalik, V. V. Astakhova, B. A. Shainyan, A. A. Tabolin, S. L. Ioffe, V. M. Muzalevskiy, E. S. Balenkova, A. V. Shastin, A. A. Tyutyunov, V. E. Boiko, S. M. Igumnov, A. D. Dilman, N. Yu. Adonin, V. V. Bardin, S. M. Masoud, D. V. Vorobyeva, S. N. Osipov, E. V. Nosova, G. N. Lipunova, V. N. Charushin, D. O. Prima, A. G. Makarov, A. V. Zibarev, B. A. Trofimov, L. N. Sobenina, K. V. Belyaeva, V. Ya. Sosnovskikh, D. L. Obydennov, S. A. Usachev, “Organofluorine chemistry: promising growth areas and challenges”, Russian Chem. Reviews, 88:5 (2019), 425–569
Valery N. Charushin, Emiliya V. Nosova, Galina N. Lipunova, Oleg N. Chupakhin, Fluorine in Heterocyclic Chemistry Volume 2, 2014, 111
E. V. Nosova, N. N. Mochul'skaya, S. K. Kotovskaya, G. N. Lipunova, V. N. Charushin, “Fluorinated benzazoles and benzazines”, Heteroatom Chemistry, 17:6 (2006), 579
E. V. Nosova, G. N. Lipunova, A. A. Laeva, V. N. Charushin, “Polyfluorobenzoyl chlorides and isothiocyanates in reactions with CH-reactive benzimidazoles”, Russ Chem Bull, 54:3 (2005), 733
Elizaveta Tsoi, Valerii N. Charushin, Emiliya V. Nosova, Galina N. Lipunova, Alexey V. Tkachev, “ChemInform Abstract: New Approach to [a]‐Fused Fluoroquinolones: The Synthesis of 5‐Oxo‐1,2,3,3a,4,5‐hexahydropyrrolo[1,2‐a]quinolines.”, ChemInform, 32:35 (2001)
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