aUral Scientific Research Institute of Technology of Medical Preparations, Ekaterinburg, Russian Federation bDepartment of Chemistry, University of Bremen, Bremen, Germany
Abstract:
The reaction of 1-amino-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-ethylcarboxylate 1 with acetoacetone in acetic acid without air yielded 1-(2-acetyl-4,5-difluorophenyl)-3-methyl-4-acetylpyrazole 3.
Document Type:
Article
Language: English
Citation:
Yu. A. Azev, E. Lork, D. Gabel, T. Duelcks, “New way of the reaction of 1-amino-6,7-difluoro-4-oxoquinolyl-3-ethylcarboxylate with acetoacetone”, Mendeleev Commun., 13:4 (2003), 184–185
Linking options:
https://www.mathnet.ru/eng/mendc4015
https://www.mathnet.ru/eng/mendc/v13/i4/p184
This publication is cited in the following 7 articles:
yulin wang, Cheng Xiong, Jiacheng Zhong, Qingfa Zhou, “Synthesis of 1,3,5-Trisubstituted Pyrazole-4-Carboxylates Through 1,3-Dipolar Cycloaddition of Nitrilimines with Allenoates”, SSRN Journal, 2022
Munish Kumar, Sharad Kumar Panday, “Pyrazole and Its Derivatives: An Excellent N-Hetrocycle with Wide Range of Biological Applications (A Review)”, Orient. J. Chem, 38:3 (2022), 568
Yulin Wang, Cheng Xiong, Jiacheng Zhong, Qingfa Zhou, “Synthesis of 1,3,5-trisubstituted pyrazole-4-carboxylates through 1,3-dipolar cycloaddition of nitrilimines with allenoates”, Tetrahedron, 115 (2022), 132790
Khalid Karrouchi, Smaail Radi, Youssef Ramli, Jamal Taoufik, Yahia N. Mabkhot, Faiz A. Al-aizari, M'hammed Ansar, “Synthesis and Pharmacological Activities of Pyrazole Derivatives: A Review”, Molecules, 23:1 (2018), 134
A. A. Boteva, O. P. Krasnykh, “The methods of synthesis, modification, and biological activity of 4-quinolones (review)”, Chem Heterocycl Comp, 45:7 (2009), 757
L. Yet, Comprehensive Heterocyclic Chemistry III, 2008, 1
Yuri A. Azev, Enno Lork, Detlef Gabel, Thomas Duelcks, “New Way of the Reaction of 1‐Amino‐6,7‐difluoro‐4‐oxoquinolyl‐3‐ethylcarboxylate with Acetoacetone.”, ChemInform, 35:3 (2004)
Contact us: