S. V. Kurmaz, I. I. Ivanova, N. S. Emelyanova, D. V. Konev, V. A. Kurmaz, N. V. Filatova, A. A. Balakina, A. A. Terentiev, “Doxorubicin compositions with biocompatible terpolymer of N-vinylpyrrolidone, methacrylic acid and triethylene glycol dimethacrylate”, Mendeleev Commun., 33:2 (2023), 255

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Mendeleev Communications, 2023, Volume 33, Issue 2, Pages 255–258
DOI: https://doi.org/10.1016/j.mencom.2023.02.034 (Mi mendc367)

This article is cited in 3 scientific papers (total in 3 papers)

Communications

Doxorubicin compositions with biocompatible terpolymer of N-vinylpyrrolidone, methacrylic acid and triethylene glycol dimethacrylate

S. V. Kurmaz^a, I. I. Ivanova^a, N. S. Emelyanova^a, D. V. Konev^a, V. A. Kurmaz^a, N. V. Filatova^a, A. A. Balakina^a, A. A. Terentiev^abc

^a Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russian Federation
^b Department of Fundamental Physical and Chemical Engineering, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
^c Moscow Region State Pedagogical University, Mytishi, Moscow Region, Russian Federation

Full-text PDF (282 kB) Citations (3)

DOI: https://doi.org/10.1016/j.mencom.2023.02.034

Graphic abstract: Doxorubicin compositions with biocompatible terpolymer of <i>N</i>-vinylpyrrolidone, methacrylic acid and triethylene glycol dimethacrylate

Abstract: Compositions of doxorubicin with a terpolymer of N-vinylpyrrolidone, methacrylic acid and triethylene glycol dimethacrylate have been prepared and investigated by UV-VIS and NMR spectroscopy, cyclic voltammetry and DFT quantum chemical modeling. Oxygen containing groups of the terpolymer and hydrogen atoms of the drug OH and NH⁺ groups form hydrogen bonds. The compositions have lower cytotoxicity in vitro compared with that of free doxorubicin

Keywords: N-vinylpyrrolidone, triethylene glycol dimethacrylate, terpolymer, doxorubicin, quantum chemical modeling, cyclic voltammetry, cytotoxicity.

Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(1.5 Mb)

Citation: S. V. Kurmaz, I. I. Ivanova, N. S. Emelyanova, D. V. Konev, V. A. Kurmaz, N. V. Filatova, A. A. Balakina, A. A. Terentiev, “Doxorubicin compositions with biocompatible terpolymer of N-vinylpyrrolidone, methacrylic acid and triethylene glycol dimethacrylate”, Mendeleev Commun., 33:2 (2023), 255–258

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This publication is cited in the following 3 articles:

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

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