Abstract:
Organized systems based on amphiphiles are discussed from the viewpoint of their application as solubilizing agents and drug and gene delivery systems with structure–activity relationships and stimuli responsibility emphasized. Special attention is paid to cationic surfactants, including gemini and naturally originated compounds. Practically important lipid formulations, i.e., liposomes and solid lipid nanoparticles, are discussed in terms of their stability, loading capacity, surface modification and therapeutic efficacy. The stimuli responsibility of formulations is analyzed and exemplified by smart supramolecular systems based on a calixarene platform.
Document Type:
Article
Language: English
Citation:
L. Ya. Zakharova, R. R. Kashapov, T. N. Pashirova, A. B. Mirgorodskaya, O. G. Sinyashin, “Self-assembly strategy for the design of soft nanocontainers with controlled properties”, Mendeleev Commun., 26:6 (2016), 457–468
Linking options:
https://www.mathnet.ru/eng/mendc2247
https://www.mathnet.ru/eng/mendc/v26/i6/p457
This publication is cited in the following 64 articles:
R. A. Kushnazarova, A. B. Mirgorodskaya, D. D. Bekrenev, A. P. Lyubina, O. A. Lenina, K. A. Petrov, A. D. Voloshina, L. Ya. Zakharova, “Supramolecular systems based on 2-hydroxyethylpiperidinium surfactants and Brij® 35: aggregation behavior, solubilization properties, and antimicrobial activity”, Russ Chem Bull, 73:3 (2024), 536
Lucia Ya. Zakharova, Elmira A. Vasilieva, Alla B. Mirgorodskaya, Sergey V. Zakharov, Rais V. Pavlov, Nadezda E. Kashapova, Gulnara A. Gaynanova, “Hydrotropes: Solubilization of nonpolar compounds and modification of surfactant solutions”, Journal of Molecular Liquids, 370 (2023), 120923
Elmira A. Vasilieva, Darya A. Kuznetsova, Farida G. Valeeva, Denis M. Kuznetsov, Lucia Ya. Zakharova, “Role of Polyanions and Surfactant Head Group in the Formation of Polymer–Colloid Nanocontainers”, Nanomaterials, 13:6 (2023), 1072
Viswanathan S. Saji, “Recent Updates on Supramolecular‐Based Drug Delivery – Macrocycles and Supramolecular Gels”, The Chemical Record, 22:7 (2022)
Julia E. Morozova, Camila R. Myaldzina, Alexandra D. Voloshina, Anna P. Lyubina, Syumbelya K. Amerhanova, Victor V. Syakaev, Albina Yu. Ziganshina, Igor S. Antipin, “Salixresorcine cavitands bearing lipophilic cationic fragments in the construction of mitochondrial-targeting supramolecular nanoparticles”, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 642 (2022), 128622
Brijesh Patel, Sneha Singh, Kushan Parikh, Vishwajit Chavda, Debes Ray, Vinod K. Aswal, Sanjeev Kumar, “Micro-Environment mapping of mole fraction inspired contrasting charged aqueous gemini micelles: A drug solubilization/release study”, Journal of Molecular Liquids, 363 (2022), 119885
R. A. Kushnazarova, A. B. Mirgorodskaya, V. A. Mikhailov, I. A. Belousova, T. M. Zubareva, T. M. Prokop'eva, A. D. Voloshina, S. K. Amerhanova, L. Ya. Zakharova, “Dicationic Imidazolium Surfactants with a Hydroxyl Substituent in the Spacer Fragment”, Russ J Gen Chem, 92:4 (2022), 659
A. B. Mirgorodskaya, A. A. Tyryshkina, R. A. Kushnazarova, D. M. Kuznetsov, L. Ya. Zakharova, “Effect of electrolytes on aggregation behavior and solubilization properties of hexadecylpiperidinium surfactants”, Russ Chem Bull, 71:9 (2022), 1907
A. V. Sybachin, D. A. Stepanova, “Modification of Multiliposomal Nanocontainers with Albumin as a Method for Increasing Their Resistance to Enzymatic Hydrolysis”, Colloid J, 83:2 (2021), 252
A. B. Mirgorodskaya, F. G. Valeeva, R. A. Kushnazarova, S. S. Lukashenko, L. Ya. Zakharova, “Catalytic Effect of Micellar Systems Based on Hydroxypiperidinium Surfactants in the Hydrolysis of a p-Nitrophenyl Phosphonate”, Kinet Catal, 62:1 (2021), 82
Polina N. Veremeeva, Olga V. Zaborova, Irina V. Grishina, Dmitriy V. Makeev, Vadim A. Timoshenko, Vladimir A. Palyulin, “Stimulus-sensitive liposomal delivery system based on new 3,7-diazabicyclo[3.3.1]nonane derivatives”, Bioorganic & Medicinal Chemistry Letters, 39 (2021), 127871
Rushana A. Kushnazarova, Alla B. Mirgorodskaya, Denis M. Kuznetsov, Anna A. Tyryshkina, Alexandra D. Voloshina, Sumbela K. Gumerova, Oxana A. Lenina, Eugeny N. Nikitin, Lucia Ya. Zakharova, “Modulation of aggregation behavior, antimicrobial properties and catalytic activity of piperidinium surfactants by modifying their head group with a polar fragment”, Journal of Molecular Liquids, 336 (2021), 116318
Alina M. Shumatbaeva, Julia E. Morozova, Victor V. Syakaev, Dmitry V. Zakharychev, Anastasia S. Sapunova, Alexandra D. Voloshina, Feruzakhon A. Bekmuratova, Vasily M. Babaev, Igor S. Antipin, “A novel salt-responsive hydrogel on the base of calixresorcinarene–mPEG amide conjugate”, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 611 (2021), 125814
Ruslan Kashapov, Alsu Ibragimova, Rais Pavlov, Dinar Gabdrakhmanov, Nadezda Kashapova, Evgenia Burilova, Lucia Zakharova, Oleg Sinyashin, “Nanocarriers for Biomedicine: From Lipid Formulations to Inorganic and Hybrid Nanoparticles”, IJMS, 22:13 (2021), 7055
I. S. Antipin, M. V. Alfimov, V. V. Arslanov, V. A. Burilov, S. Z. Vatsadze, Ya. Z. Voloshin, K. P. Volcho, V. V. Gorbatchuk, Yu. G. Gorbunova, S. P. Gromov, S. V. Dudkin, S. Yu. Zaitsev, L. Ya. Zakharova, M. A. Ziganshin, A. V. Zolotukhina, M. A. Kalinina, E. A. Karakhanov, R. R. Kashapov, O. I. Koifman, A. I. Konovalov, V. S. Korenev, A. L. Maksimov, N. Zh. Mamardashvili, G. M. Mamardashvili, A. G. Martynov, A. R. Mustafina, R. I. Nugmanov, A. S. Ovsyannikov, P. L. Padnya, A. S. Potapov, S. L. Selektor, M. N. Sokolov, S. E. Solovieva, I. I. Stoikov, P. A. Stuzhin, E. V. Suslov, E. N. Ushakov, V. P. Fedin, S. V. Fedorenko, O. A. Fedorova, Yu. V. Fedorov, S. N. Chvalun, A. Yu. Tsivadze, S. N. Shtykov, D. N. Shurpik, M. A. Shcherbina, L. S. Yakimova, “Functional supramolecular systems: design and applications”, Russian Chem. Reviews, 90:8 (2021), 895–1107
Alla B. Mirgorodskaya, Rushana A. Kushnazarova, Svetlana S. Lukashenko, Eugeny N. Nikitin, Kirill O. Sinyashin, Liliya M. Nesterova, Lucia Ya. Zakharova, “Carbamate-bearing surfactants as effective adjuvants promoted the penetration of the herbicide into the plant”, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 586 (2020), 124252
Ruslan Kashapov, Gulnara Gaynanova, Dinar Gabdrakhmanov, Denis Kuznetsov, Rais Pavlov, Konstantin Petrov, Lucia Zakharova, Oleg Sinyashin, “Self-Assembly of Amphiphilic Compounds as a Versatile Tool for Construction of Nanoscale Drug Carriers”, IJMS, 21:18 (2020), 6961
A. B. Mirgorodskaya, R. A. Kushnazarova, S. S. Lukashenko, L. Ya. Zakharova, “Mixed Micellar Solutions of Hexadecylpiperidinium Surfactants and Tween 80: Aggregation Behavior and Solubilizing Properties”, Russ. J. Phys. Chem., 94:9 (2020), 1902
M.M. Vorob'ev, O.V. Sinitsyna, “Degradation and assembly of β-casein micelles during proteolysis by trypsin”, International Dairy Journal, 104 (2020), 104652
Alla B. Mirgorodskaya, Darya A. Kuznetsova, Rushana A. Kushnazarova, Dinar R. Gabdrakhmanov, Nataliya A. Zhukova, Svetlana S. Lukashenko, Anastasiia S. Sapunova, Alexandra D. Voloshina, Oleg G. Sinyashin, Vakhid A. Mamedov, Lucia Y. Zakharova, “Soft nanocarriers for new poorly soluble conjugate of pteridine and benzimidazole: Synthesis and cytotoxic activity against tumor cells”, Journal of Molecular Liquids, 317 (2020), 114007
Contact us: