Abstract:
Photophysical parameters, photostability, aggregation behavior and photochemical activity of a new chlorin p6-based photosensitizer in micellar surfactant solutions were estimated. Despite the low fluorescence quantum yields, this compound demonstrates high photostability, and its photodynamic activity in micellar systems is comparable to that of the commercial photosensitizer Fotoditazin®, which makes this chlorin p6 derivative suitable for the interstitial photodynamic therapy of solid tumors.
Document Type:
Article
Language: English
Citation:
M. A. Gradova, I. I. Ostashevskaya, O. V. Gradov, A. V. Lobanov, V. S. Lebedeva, A. F. Mironov, “Photophysical properties and photodynamic activity of 13,15-N-methoxy-cycloimide chlorin p6 methyl ester in micellar surfactant solutions”, Mendeleev Commun., 28:6 (2018), 589–591
Linking options:
https://www.mathnet.ru/eng/mendc1845
https://www.mathnet.ru/eng/mendc/v28/i6/p589
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S. V. Kurmaz, I. V. Ul'yanov, N. S. Emel'yanova, “Compositions of aluminum phthalocyanine with amphiphilic N-vinylpyrrolidone copolymers and their nanosized structures in aqueous media. Experimental and theoretical research”, Russ Chem Bull, 74:1 (2025), 210
Margarita A. Gradova, Oleg V. Gradov, Anton V. Lobanov, Tamara G. Movchan, Elena V. Plotnikova, Andrey Yu. Chernyadyev, Olga M. Startseva, Dmitry V. Belykh, “Photophysical properties and aggregation behavior of diethylene glycol substituted pyropheophorbide-a in cationic surfactant solutions”, J. Porphyrins Phthalocyanines, 26:11 (2022), 708
A. V. Kustov, M. A. Krestyaninov, S. O. Kruchin, O. V. Shukhto, T. V. Kustova, D. V. Belykh, I. S. Khudyaeva, O. I. Koifman, P. B. Razgovorov, D. B. Berezin, “Interaction of cationic chlorin photosensitizers with non-ionic surfactant Tween 80”, Mendeleev Commun., 31:1 (2021), 65–67
Margaret A. Gradova, Oleg V. Gradov, Kseniya A. Zhdanova, Natalya A. Bragina, Anton V. Lobanov, “Self-assembly of amphiphilic meso-aryl-substituted porphyrin derivatives in the presence of surfactants”, J. Porphyrins Phthalocyanines, 24:04 (2020), 505
N. S. Kuzmina, V. F. Otvagin, L. V. Krylova, A. V. Nyuchev, Yu. V. Romanenko, O. I. Koifman, I. V. Balalaeva, A. Yu. Fedorov, “Synthesis and antiproliferative activity of new chlorin e6 glycoconjugates”, Mendeleev Commun., 30:2 (2020), 159–161
M. R. Ibatullina, E. P. Zhil´tsova, S. S. Lukashenko, V. I. Kovalenko, I. I. Vandyukova, M. P. Kutyreva, L. Ya. Zakharova, “Mixed micellar systems of metal complexes of alkylated N-methyl-d-glucamines with hexadecyltrimethylammonium bromide”, Russ Chem Bull, 68:2 (2019), 424
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