Abstract:
A multicomponent one-pot environmentally benign transformation of salicylaldehydes, kojic acid and malononitrile or its derivativies, catalyzed by sodium acetate, in a small amount of ethanol results in efficient formation of new substituted 2-amino-4-[3-hydroxy-6-(hydroxymethyl)-4-oxo-4H-pyran-2-yl]-4H-chromene-3-carbonitriles or -3-carboxylates in 75–96% yields.
Citation:
M. N. Elinson, A. N. Vereshchagin, Yu. E. Anisina, S. K. Krymov, A. N. Fakhrutdinov, M. P. Egorov, “Multicomponent assembling of salicylaldehydes, kojic acid and malonic acid derivatives”, Mendeleev Commun., 29:5 (2019), 581–583
Linking options:
https://www.mathnet.ru/eng/mendc1598
https://www.mathnet.ru/eng/mendc/v29/i5/p581
This publication is cited in the following 9 articles:
Amol A. Nagargoje, Mubarak H. Shaikh, Bapurao B. Shingate, “Curcumin‐based bioactive heterocycles derived via multicomponent reactions”, Archiv der Pharmazie, 356:8 (2023)
Yuliya E. Ryzhkova, Michail N. Elinson, Anatoly N. Vereshchagin, Varvara M. Kalashnikova, Victor A. Korolev, Fedor V. Ryzhkov, Mikhail P. Egorov, “Green electrocatalytic Assembling of Salicylaldehydes, Kojic Acid, and Malonic Acid Derivatives into 2‐amino‐4H‐chromenes as Potent Anti‐inflammatory Agents”, ChemistrySelect, 7:39 (2022)
Ghodsi Mohammadi Ziarani, Fatemeh Mohajer, “An Overview of Quantitative and Qualitative Approaches on the Synthesis of Heterocyclic Kojic Acid Scaffolds through the Multi-Component Reactions”, HETEROCYCLES, 102:2 (2021), 211
Ankita Chaudhary, “Recent Advances in the Exploitation of Kojic Acid in Multicomponent Reactions”, COC, 24:14 (2020), 1643
Xiaoyi Yue, Olga A. Storozhenko, Alexey A. Festa, Elena A. Sorokina, Alexey V. Varlamov, Leonid G. Voskressensky, “Microwave-assisted sequential three-component synthesis of pyrrolyl-substituted chromeno[2,3-c]isoquinolin-5-amines”, Chem Heterocycl Comp, 56:4 (2020), 495
W. Bao, H. Kossen, J. Richards, U. Schneider, Catalysis with Earth-abundant Elements, 2020, 1
Fedor V. Ryzhkov, Yuliya E. Ryzhkova, Michail N. Elinson, Anatoly N. Vereshchagin, Victor A. Korolev, Mikhail P. Egorov, “Quadruple Bond Forming Multicomponent Approach to 5-(3-chromenyl)-5H-chromeno[2,3-b]pyridines and Its Interaction with the Neuropeptide Y1 Receptor”, Chem Heterocycl Comp, 56:12 (2020), 1560
M. N. Elinson, A. N. Vereshchagin, Yu. E. Anisina, N. A. Leonova, M. P. Egorov, “On water noncatalytic tandem Knoevenagel–Michael reaction of aldehydes, N,N'-dimethylbarbituric acid and cyclohexane-1,3-diones”, Mendeleev Commun., 30:1 (2020), 15–17
M. N. Elinson, A. N. Vereshchagin, Yu. E. Ryzhkova, S. K. Krymov, N. A. Leonova, A. S. Goloveshkin, M. P. Egorov, “Electrocatalytic one-pot multicomponent assembly of aldehydes, 2,4-dihydro-3H-pyrazol-3-ones and kojic acid”, Mendeleev Commun., 30:2 (2020), 223–225
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