S. Gundala, M. R. Guda, A. F. Khasanov, D. S. Kopchuk, A. P. Krinochkin, S. Santra, G. V. Zyryanov, P. Venkatapuram, J. R. Garcia, V. N. Charushin, “A PASE-based approach towards 12-(1H-1,2,3-triazol-1-yl)-indolo[2,1-a]isoquinolines via the reaction of 3-(isoquinolin-1-yl)-1,2,4-triazines with benzyne”, Mendeleev Commun., 29:4 (2019), 369

Loading [MathJax]/jax/output/SVG/config.js

Mendeleev Communications

RUS ENG

JOURNALS PEOPLE ORGANISATIONS CONFERENCES SEMINARS VIDEO LIBRARY PACKAGE AMSBIB

JavaScript is disabled in your browser. Please switch it on to enable full functionality of the website

	General information
	Latest issue
	Archive

	Search papers
	Search references

	RSS
	Latest issue
	Current issues
	Archive issues
	What is RSS

Mendeleev Commun.:
Year:
Volume:
Issue:
Page:
	Find

Personal entry:
Login:
Password:
	Save password
	Enter
	Forgotten password?
	Register

Mendeleev Communications, 2019, Volume 29, Issue 4, Pages 369–371
DOI: https://doi.org/10.1016/j.mencom.2019.07.002 (Mi mendc1525)

This article is cited in 9 scientific papers (total in 9 papers)

Communications

A PASE-based approach towards 12-(1H-1,2,3-triazol-1-yl)-indolo[2,1-a]isoquinolines via the reaction of 3-(isoquinolin-1-yl)-1,2,4-triazines with benzyne

S. Gundala^ab, M. R. Guda^ac, A. F. Khasanov^ad, D. S. Kopchuk^ad, A. P. Krinochkin^ad, S. Santra^a, G. V. Zyryanov^ad, P. Venkatapuram^b, J. R. Garcia^c, V. N. Charushin^ad

^a Institute of Chemical Engineering, Ural Federal University, Ekaterinburg, Russian Federation
^b Department of Chemistry, Sri Venkateswara University, Andhra Pradesh, India
^c Departamento de Química, Universidade Estadual de Ponta Grossa, Paraná, Brazil
^d I.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russian Federation

Full-text PDF (368 kB) Citations (9)

DOI: https://doi.org/10.1016/j.mencom.2019.07.002

Graphic abstract: A PASE-based approach towards 12-(1<i>H</i>-1,2,3-triazol-1-yl)-indolo[2,1-<i>a</i>]isoquinolines <i>via</i> the reaction of 3-(isoquinolin-1-yl)-1,2,4-triazines with benzyne

Abstract: 12-(1H-1,2,3-Triazol-1-yl)indolo[2,1-a]isoquinolines are prepared in 51–56% yields using a PASE (pot, atom, step, economic)-based approach, namely, by the reaction between available 5-R-6-Ar-3-(isoquinolin-1-yl)-1,2,4-triazines and in situ generated benzyne. A mechanism comprising domino-transformation was suggested, and the structure of one key product was confirmed by a single crystal X-ray diffraction analysis.

Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(909.6 Kb)

Citation: S. Gundala, M. R. Guda, A. F. Khasanov, D. S. Kopchuk, A. P. Krinochkin, S. Santra, G. V. Zyryanov, P. Venkatapuram, J. R. Garcia, V. N. Charushin, “A PASE-based approach towards 12-(1H-1,2,3-triazol-1-yl)-indolo[2,1-a]isoquinolines via the reaction of 3-(isoquinolin-1-yl)-1,2,4-triazines with benzyne”, Mendeleev Commun., 29:4 (2019), 369–371

Linking options:

https://www.mathnet.ru/eng/mendc1525

https://www.mathnet.ru/eng/mendc/v29/i4/p369

This publication is cited in the following 9 articles:

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

Statistics & downloads:
Abstract page:	58
Full-text PDF :	7

Registration to the website

Logotypes