D. V. Belyaev, D. L. Chizhov, M. I. Kodess, M. A. Ezhikova, G. L. Rusinov, V. N. Charushin, “Synthesis of 2-(polyfluoromethyl)pyrimido-[1,2-a]benzimidazole-4-carbaldehyde derivatives”, Mendeleev Commun., 29:3 (2019), 249

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Mendeleev Communications, 2019, Volume 29, Issue 3, Pages 249–251
DOI: https://doi.org/10.1016/j.mencom.2019.05.002 (Mi mendc1485)

This article is cited in 5 scientific papers (total in 5 papers)

Communications

Synthesis of 2-(polyfluoromethyl)pyrimido-[1,2-a]benzimidazole-4-carbaldehyde derivatives

D. V. Belyaev^a, D. L. Chizhov^a, M. I. Kodess^ab, M. A. Ezhikova^a, G. L. Rusinov^ab, V. N. Charushin^ab

^a I.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russian Federation
^b Institute of Chemical Engineering, Ural Federal University, Ekaterinburg, Russian Federation

Full-text PDF (299 kB) Citations (5)

DOI: https://doi.org/10.1016/j.mencom.2019.05.002

Graphic abstract: Synthesis of 2-(polyfluoromethyl)pyrimido-[1,2-<i>a</i>]benzimidazole-4-carbaldehyde derivatives

Abstract: A simple and efficient synthesis of 2-R^F-pyrimido[1,2-a]benzimidazole-4-carbaldehyde derivatives comprises the reaction between 3-(polyfluoroacetyl)pyruvaldehyde dimethyl acetals and 2-aminobenzimidazole. The effects of fluorinated substituents in 3-(polyfluoroacetyl)pyruvaldehyde dimethyl acetals and the reaction conditions on regiochemical outcome of this reaction have been estimated.

Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(1.2 Mb)

Citation: D. V. Belyaev, D. L. Chizhov, M. I. Kodess, M. A. Ezhikova, G. L. Rusinov, V. N. Charushin, “Synthesis of 2-(polyfluoromethyl)pyrimido-[1,2-a]benzimidazole-4-carbaldehyde derivatives”, Mendeleev Commun., 29:3 (2019), 249–251

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https://www.mathnet.ru/eng/mendc/v29/i3/p249

This publication is cited in the following 5 articles:

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

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