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Mendeleev Communications, 2024, Volume 34, Issue 3, Pages 365–368
DOI: https://doi.org/10.1016/j.mencom.2024.04.017
(Mi mendc130)
 

Communications

Effect of L- or D,L-leucine content on self-assembly and properties of its amphiphilic copolymers with L-lysine

E. G. Korzhikova-Vlakhab, N. N. Zashikhinab, E. G. Stulovaa, A. Yu. Dzhuzhab, V. A. Korzhikov-Vlakha

a Institute of Chemistry, St. Petersburg State University, St. Petersburg, Russian Federation
b Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russian Federation
Abstract: Copolymers of l-lysine and l/d,l-leucine differing in amino acid composition were synthesized and characterized for their self-assembly into nanoparticles. The effect of polypeptide composition on critical aggregation concentration, hydrodynamic diameter of nanoparticles, their stability and cytotoxicity was explored and discussed.
Keywords: copolymers, lysine, leucine, amphiphilic polypeptides, self-assembly, critical aggregation concentration, nanoparticles.
Document Type: Article
Language: English
Supplementary materials:
Supplementary_data_1.pdf (306.0 Kb)


Citation: E. G. Korzhikova-Vlakh, N. N. Zashikhina, E. G. Stulova, A. Yu. Dzhuzha, V. A. Korzhikov-Vlakh, “Effect of L- or D,L-leucine content on self-assembly and properties of its amphiphilic copolymers with L-lysine”, Mendeleev Commun., 34:3 (2024), 365–368
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