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Mendeleev Communications, 2020, Volume 30, Issue 3, Pages 347–349
DOI: https://doi.org/10.1016/j.mencom.2020.05.029 (Mi mendc1193) 		 
This article is cited in 8 scientific papers (total in 8 papers)

Communications

Synthesis of new physiologically active (2-oxoimidazolidin-5-yl)indoles

L. A. Sviridovaa, P. S. Protopopovab, M. G. Akimovc, M. S. Dudinac, E. K. Melnikovaab, K. A. Kochetkovbd

a Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
b A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation
c M.M. Shemyakin–Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
d D.Mendeleev University of Chemical Technology of Russia, Moscow, Russian Federation
Full-text PDF (288 kB) Citations (8)
DOI: https://doi.org/10.1016/j.mencom.2020.05.029
Abstract: Boron trifluoride-catalyzed amidoalkylation of indole derivatives with 5-hydroxy-1-phenylimidozolidin-2-one affords new biheterocycles with a direct C–C bond. Among them, 3- or 2-(2-oxoimidazolidin-5-yl)indoles manifest antiinflammatory activity with relatively low toxicity.
Keywords: amidoalkylation, biheterocycles, 3- or 2-(2-oxoimidazolidin-5-yl)indoles, anti-inflammatory activity, indoles, imidazolylindoles.
Document Type: Article
Language: English
Supplementary materials:
Supplementary_data_1.pdf (1.4 Mb)


Citation: L. A. Sviridova, P. S. Protopopova, M. G. Akimov, M. S. Dudina, E. K. Melnikova, K. A. Kochetkov, “Synthesis of new physiologically active (2-oxoimidazolidin-5-yl)indoles”, Mendeleev Commun., 30:3 (2020), 347–349
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  • https://www.mathnet.ru/eng/mendc/v30/i3/p347
    • This publication is cited in the following 8 articles:
    Citing articles in Google Scholar: Russian citations, English citations
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